New publication in JBC
Congratulations Júlia and Stefan for their publication in JBC on J-domains and Hsp70: Aragonès Pedrola J, Rüdiger SGD. Double J-domain piloting of an Hsp70 substrate. J. Biol. Chem. 2021 100717 Link
Research on how proteins (mis)fold
Congratulations Júlia and Stefan for their publication in JBC on J-domains and Hsp70: Aragonès Pedrola J, Rüdiger SGD. Double J-domain piloting of an Hsp70 substrate. J. Biol. Chem. 2021 100717 Link
Congratulations Marcel and Ineke for their publication in JBC on the CFTR P67L variant: Sabusap CM, Joshi D, Simhaev L, Oliver KE, Senderowitz H, van Willigen M, Braakman I, Rab A, Sorscher EJ, Hong JS. The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue. J. … Read more
Joseline received a permanent contract at Utrecht University from April onwards. Congratulations Joseline on your permanent position!
Congratulations Bertrand, Marcel, Floor, Magda, Tamara, Ann, Peter and Ineke for their publication in JMB on co-translational folding of the first CFTR domains: Kleizen B, van Willigen M, Mijnders M, Peters FM, Grudniewska MK, Hillenaar TM, Thomas AS, Kooijman L, Peters KW, Frizzell R, van der Sluijs P, Braakman I. Co-translational folding of the first … Read more
Ineke Braakman receives €50,000 from the Dutch Cystic Fibrosis Patient organization (NCFS) to research the effect of intragenic modifiers on CFTR biosynthesis. Although CF is caused by a defect in only a single gene, CF patients with the same mutation in CFTR show significant variation in disease progression and response to therapy, such as the … Read more