People

Scientific Staff

Ineke Braakman
+31 30 253 2759
i.braakman@uu.nl
Office: O.705


Stefan Rüdiger
+31 30 253 3394
s.g.d.rudiger@uu.nl
Office: O.704


Peter van der Sluijs
+31 30 253 2490
p.vandersluijs1@uu.nl
Office: O.702


Bertrand Kleizen
+31 30 253 2490
b.kleizen@uu.nl
Office: O.702


Adabella van der Zand

a.vanderzand@uu.nl


Support

Marjolein Smithuis
+31 30 253 2184
science.folding@uu.nl
Office: O.703
Secretary


Joseline Houwman
+31 30 253 3898
cpc@uu.nl
Office: O.703
Scientific assistant

Postdoctoral researchers

PhD candidates

Laura Tadé
+31 30 253 3752
l.tade@uu.nl
Office: O.709


I want to know whether CFTR is only active at the cell surface or also in other cell compartments and when/where it acquires the structure that allows its function.


Margreet Koopman
+31 30 253 4105
m.b.koopman@uu.nl
Office: O.707

I focus on the role of molecular chaperones – such as Hsp70 and Hsp90 – and their role in the aggregation process of Tau, a protein involved in Alzheimer’s Disease.

Júlia Aragones Pedrola
+31 30 253 3841
j.aragonespedrola@uu.nl
Office: O.710
Development of a strategy to target protein aggregation diseases, based on mimicking the role of molecular chaperones in the protein quality control.

Magdalena Wawrzyniuk
+31 30 253 2490
m.wawrzynuik@uu.nl
Office: O.702

My research focuses on how Hsp90 selects its client proteins, as known Hsp90 binding partners recruit from various protein families and do not share functional or structural similarities.


Tamara Hillenaar
+31 30 253 3610
m.j.h.hillenaar@uu.nl
Office: O.706

The aim of my research is to determine for each CFTR2 disease-causing mutant to which available (pre)clinical drugs they respond at the CFTR protein level.


Jisu Im
+31 30 253 3752
j.im@uu.nl
Office: O.709

My project investigates how CFTR transmembrane domains assemble, and see how chaperones help with the assembly of these transmembrane domains with each other and nucleotide binding domains.


Technicians

Danny Schildknegt
+31 30 253 3841
d.schildknegt@uu.nl
Office: O.710

I am interested in a set of small endoplasmic reticulum localized chaperones, called the canopy family and their role in proteins folding, B cell differentiation and antibody secretion.


Guus van Zadelhoff
+31 30 253 3752
g.vanzadelhoff@uu.nl
Office: O.709

I develop/modify analysis techniques to study protein folding of model oxidative proteins and folding factors, in vivo and in vitro by short and long radioactive metabolic labelling


Senna Hiensch
+31 30 253 3601
s.hiensch@uu.nl
Office: O.706

My research is about comparing genetic disease causing protein mutants to their wildtype variant by limited proteolysis and see if chaperones are able to stabilize these mutants.



Ann Thomas
+31 30 253 3841
a.s.thomas@uu.nl
Office: O.710

My project aims to investigate the correlation between translation rate and CFTR folding.

Students

Sam Jones
+31 30 253 . . . .
s.j.jones@students.uu.nl
Office: O.707


Guests

Maarten Egmond

m.r.egmond@uu.nl