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I focus on aggregation-prone proteins linked to neurodegeneration. I am especially interested in understanding how Hsp90 can modulate Tau aggregation and its associated interactome.
My research focuses on the interplay between the chaperones Hsp70 and Hsp90, with emphasis on the purpose of Hsp90 and the function of the Hsp70/Hsp90 folding cascade.
I focus on the role of molecular chaperones – such as Hsp70 and Hsp90 – and their role in the aggregation process of Tau, a protein involved in Alzheimer’s Disease.
My research focuses on how Hsp90 selects its client proteins, as known Hsp90 binding partners recruit from various protein families and do not share functional or structural similarities.