Cellular Protein Chemistry is part of the Bijvoet Center for Biomolecular Research and the Chemistry Department of Utrecht University.
Maintaining the natural shape of proteins is essential for life. Failure to do so is origin of lethal, incurable diseases such as Cystic Fibrosis, Alzheimer, Parkinson, ALS, or cancer. Common to those diseases are fatal distortions in protein shape. Human life therefore depends on a defense system that maintains the shape of our proteins, the strongly regulated network of chaperones and folding enzymes. Why does this network fail in disease? Our work is dedicated to the origin of protein failure diseases and the regulation and mechanisms of our natural defense systems.
Currently our teaching activities include leading roles in the Bachelor Chemistry, the new combination study Molecular Life Sciences, the Master Molecular and Cellular Life Sciences and the Summer School Exploring Nature’s Molecular Machines.