The Braakman & van der Sluijs group recently published a video article explaining how to do a radioactive pulse-chase experiments, including all the necessary tips and tricks! Analysis of Protein Folding, Transport, and Degradation in Living Cells by Radioactive Pulse Chase Starring: Bertrand, Guus and Ying
2019 is off with a good start with two publications! Morán Luengo T, Mayer MP, Rüdiger SGD. The Hsp70-Hsp90 chaperone cascade in protein folding. Trends Cell Biol. 2019 29(2):164-177. Link van Willigen M, Vonk AM, Yeoh HY, Kruisselbrink E, Kleizen B, van der Ent CK, Egmond MR, de Jonge HR, Braakman I, Beekman JM, van … Read moreNew publications
In addition to an article in JMB, Stefan also snagged the cover image: 03 May 2018 – Volume 70, Issue 3 On the cover: Proteins find their way into their active three-dimensional structure on a rugged energy hypersurface. In the cell, molecular chaperones assist protein folding. In this issue of Molecular Cell, Morán Luengo et al. … Read moreCPC artwork as cover for JMB!
In addition to an article in Mol Cell (03 May 2018 – Volume 70, Issue 3), Stefan also snagged the cover image:
The proteins in our cells are produced as long chains of amino acids that must fold precisely into their final shape. The key players in this folding process are the so-called molecular chaperones; protein helpers that make sure this process is successful. Researchers from Utrecht University, in close collaboration with colleagues from Heidelberg University, have … Read moreChaperones just prepare proteins for folding on their own