Research on how proteins (mis)fold
The 14th Young Investigators meeting of the European Cystic Fibrosis Society was held form 26-28 February in Paris. This meeting aims at strengthening the skills and knowledge of young scientists involved in CF cutting-edge research. Jisu attended this meeting with a poster and won the Poster Pitch prize! She was presented with the award by … Read more
Stefan and Luca recently published an article in Nature Communications, revealing that arginine π-stacking drives binding of certain proteins tend to Tau fibrils. The paper was covered on BNR radio in a short podcast (4 min) and on the UU website.
16 and 17 December the annual Chaperone Club meeting was held in Manchester, UK. It was a combined meeting of the Dutch and British clubs and an anniversary for both (20th for the Dutch, 30th for the British). It was a great anniversary meeting with high-quality presentations from students and post docs and three exceptional … Read more
Congratulations Stefan and Lena for their publication in Nature on α-synuclein regulation: BM Burmann, JA Gerez, I Matečko-Burmann, S Campioni, P Kumari, D Ghosh, A Mazur, EE Aspholm, D Šulskis, M Wawrzyniuk, T Bock, A Schmidt, SGD Rüdiger, R Riek & S Hiller. Regulation of α-synuclein by chaperones in mammalian cells. Nature 2020 577:127-32 Link
From the UU website Cellular protein scientist Stefan Rüdiger has been granted funding by Alzheimer Nederland. He will receive € 200,000 for research on the aggregation of the Tau protein, a hallmark of Alzheimer’s disease. He aims to develop a chaperone-mimetic removal strategy for Tau aggregation. The hallmark of Alzheimer’s disease is the death of neurons … Read more