Publications

In addition to an article in Mol Cell (03 May 2018 – Volume 70, Issue 3), Stefan also snagged the cover image:

The proteins in our cells are produced as long chains of amino acids that must fold precisely into their final shape. The key players in this folding process are the so-called molecular chaperones; protein helpers that make sure this process is successful. Researchers from Utrecht University, in close collaboration with colleagues from Heidelberg University, have … Read more

Insight in derailing cancer cell offers new clues for cancer treatment Scientists at UMC Utrecht and Utrecht University have discovered that genetic changes in the DNA of cancer cells can lead to the formation of small protein aggregates. These aggregates subsequently disable a whole network of tumour-suppressing proteins, thereby causing cancer growth. This new insight … Read more

Master’s student Dominique Hagemans and Bachelor’s student Ianthe van Belzen are first and second authors of a publication in Frontiers that has been viewed more than 190 times in 3 weeks. Together, they have developed a script that can be used in computer simulations to highlight atoms in large proteins in different colours depending on … Read more

Principle plays a role in nearly all processes in our cells After nine years of research, chemists of Utrecht University together with colleagues in Europe and America have solved the mystery of how one of the most important chaperone proteins in our cells, Hsp90, selects its client proteins. Hsp90 plays a role in nearly all … Read more