2023
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Unfolding IRE1α/β: How IRE1 accommodates stress at mucosal surfaces
Mariska Simpson, August 2023, Braakman, Lencer, and Grey
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CFTR folding in health and disease
Tamara Hillenaar, April 2023, Braakman and van der Sluijs
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2022
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Molecular chaperones in neurodegeneration
Margreet Koopman, April 2022, Rüdiger
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2020
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Uncovering CFTR folding through patient mutations
Marcel van Willigen, September 2020, Braakman and van der Sluijs
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Folding of CFTR transmembrane domains in the endoplasmic reticulum
Hiu Ying Yeoh, March 2020, Braakman and van der Sluijs
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2019
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Control of Tau Aggregation by Molecular Chaperones
Luca Ferrari, June 2019, Rüdiger
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The mechanism of action of molecular chaperones
Tania Morán Luengo, April 2019, Rüdiger
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Unraveling the puzzle of CFTR domain folding and assembly
Marjolein Mijnders, February 2019, Braakman, van der Sluijs and Kleizen
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Oxidative folding of influenza virus hemagglutinin subtypes
Doron Gollnast, January 2019, Braakman and van der Sluijs
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2018
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Stories of a Diva – Interactions of the Hsp90 chaperone machinery with client proteins
Martina Rádli, March 2018, Rüdiger
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2017
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CFTR folding and the molecular chaperone Hsp90
Daniel Mesquita da Fonseca, November 2017, Braakman, van der Sluijs and Kleizen
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Role of CNPY5 in B cell activation and immunoglobulin production
Naomi Lodder, October 2017, Braakman and van der Sluijs
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Re-evaluation of PDI function in mammalian cells
Anna Chatsisvili, June 2017, Braakman
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Folding of the HIV-1 envelope glycoprotein in the ER
Nicholas McCaul, May 2017, Braakman
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2016
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Uncovering function of Grp94, the endoplasmic reticulum Hsp90
Abhinav Pandey, February 2016, Braakman
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Sources of artefacts in biomolecular NMR spectroscopy
Andrea Vavrinská, January 2016, Braakman and Trantirek
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2014
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HIV-1 envelope glycoprotein gp160 – biosynthesis, structure and function
Matthias Quandte, June 2014, Braakman
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Folding of influenza virus hemagglutinin in insect cells
Xin Li, April 2014, Braakman
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Folding of the LDL receptor dissected
Sabine Gremme, February 2014, Braakman
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2013
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Large disordered regions guard Wnt signalling
David-Paul Minde, November 2013, Rüdiger
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2012
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Molecular mechanisms regulating exocytosis from post Golgi compartments
Emma Martínez Sánchez, July 2012, van der Sluijs
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Structural dynamics of the Hsp90 chaperone machine
Tatiana Didenko, May 2012, Rüdiger
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2011
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Axin tumour suppressor function and dysfunction in the Wnt/β-catenin signalling pathway
Zeinab Anvarian, October 2011, Rüdiger
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Protein scaffolding in the Wnt/β signalling regulation
Maria Noutsou, October 2011, Rüdiger
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The Hsp90 chaperone in action: following the ATP cycle of a molecular machine
Elif Karagöz, April 2011, Rüdiger
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The role of munc13-4 in release of secretory lysosomes from hematopoietic cells
Edo Elstak, July 2012, van der Sluijs
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2010
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Helping hands – Molecular chaperones for protein kinases
Sandra Kling, December 2010, Rüdiger
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Hsp90 molecular chaperone: The effect on breast cancer cell invasion and functional interactions with Aha1 co-chaperone
Jakub Urbański, September 2010, Braakman, Utrecht/Warsaw
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Folding defects and rescue mechanisms of DF508 CFTR
Hanneke Hoelen, June 2010, Braakman
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2009
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Grp94 – between ER resident chaperone and UPR regulator
Viorica Lastun, August 2009, Braakman
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2008
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Mechanisms of secretory lysosome exocytosis in hematopoietic cells
Maaike Neeft, September 2008, van der Sluijs
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Defining functional interaction networks of rab GTPases using proteomics
Thijs van Vlijmen, Juni 2008, van der Sluijs
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2007
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rab GTPases during mitosis
Claudia Fila, December 2007, van der Sluijs
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Molecular and functional characterization of BAIAP3 and munc13-4
Marnix Wieffer, September 2007, van der Sluijs
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The endoplasmic reticulum: a dynamic protein folding environment
Chantal Christis, May 2007, Braakman
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rab4 and its interacting proteins in endosome function
Ioana Popa, May 2007, van der Sluijs
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2006
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Rabip4′ in protein sorting from endosomes
Viorica Ivan, Juni 2007, van der Sluijs
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Initial characterization of folding, structure, and function of the new ER protein smERp1
Nicole Hafkemeijer, March 2006, Braakman
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2005
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Oxidative protein folding in the ER: the roles of PDI, Ero1a and ERp44
Jenny Smit, November 2005, Braakman
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Folding of two viral glycoproteins: Influenza Hemagglutinin and HIV-1 Envelope
Marije Liscaljet, May 2005, Braakman
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Folding of CFTR at the endoplasmic reticulum
Bertrand Kleizen, March 2005, Braakman
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2004
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Recessive and dominant nephrogenic diabetes insipidus – novel molecular and cellular mechanisms
Paul JM Savelkoul, December 2004, van der Sluijs
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CD2-associated protein
Ari Ora, May 2004, van der Sluijs
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2003
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Intra- and extracellular factors involved in the trafficking of the aquaporin-2 water channel
Bas van Balkom, December 2003, van der Sluijs
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ER expansion and folding of viral glycoproteins
Claudia Maggioni, November 2003, Braakman
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Chaperones and peroxisomes
Wim de Jonge, October 2003, Braakman
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Versatility of the ER folding factory and the making & breaking of disulfide bonds
Eelco van Anken, October 2003, Braakman
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Synthesis and sorting of the aquaproin-2 water channel
Giel Hendriks, September 2003, van der Sluijs
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2002
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Rab GTPases and their binding proteins in the regulation of endocytosis
Magdalena Deneka, November 2002, van der Sluijs
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Folding of the LDL receptor in the endoplasmic reticulum
Annemieke Jansens, September 2002, Braakman
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2001
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Folding of the Human Immunodeficiency virus Envelope glycoprotein in the endoplasmic reticulum
Aafke Land, June 2001, Braakman
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The role of the small GTPase rab4 in endosome function
Karin Mohrmann, Juni 2001, van der Sluijs
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A role for glycosphingolipids in protein sorting
Hein Sprong, May 2001, van der Sluijs
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