Recent publications at CPC
Joshi U, Houwman JA, van der Sluijs P. Lysosomes nor mice move forward without Borcs7. Trends Cell Biol. 2018 28(10):761-763. Link
Nag S, Rani S, Mahanty S, Bissig C, Arora P, Azevedo C, Saiardi A, van der Sluijs P, Delevoye C, van Niel G, Raposo G, Setty SRG. Rab4A organizes endosomal domains for sorting cargo to lysosome-related organelles. J Cell Sci. 2018 131(18). Link
Radli M, Rüdiger SG. Dancing with the diva: Hsp90-client interactions J Mol Biol. 2018 14:430 Link
Feige MJ, Braakman I, Hendershot LM. Disulfide bonds in protein folding and stability. Oxidative folding of proteins: basic principles, cellular regulation and engineering. 2018 Chapter 1.1. Link
Mall MA, Hwang TC, Braakman I. Cystic fibrosis research topics featured at the 14th ECFS Basic Science Conference: Chairman’s summary. J Cyst Fibros. 2018 17(2S):S1-S4. Link
Morán Luengo T, Kityk R, Mayer MP, Rüdiger SGD. Hsp90 breaks the deadlock of the Hsp70 chaperone system. Mol Cell. 2018 70:545-552 (cover story). Link
Bin NR, Ke Ma, Tien CW, Wang S, Zhu D, Park S, Turlova E, Sugita K, Shirakawa R, van der Sluijs P, Horiuchi H, Sun HS, Monnier P, Gaisano H, Sugita S. Munc13-4 is a major Ca2+ sensor for cytotoxic granule exocytosis in NK cells. J. Immunol. 2018 20:700-13doi: 10.4049/jimmunol.1800426. Link
Dhekne HS, Pylypenko O, Overeem AW, Ferreira RJ, van der Velde KJ, Rings EHHM, Posovszky C, Swertz MA, van der Sluijs P, Houdusse A, van IJzendoorn SCD. MYO5B, STX3, and STXBP2 mutations reveal a common disease mechanism that unifies a subset of congenital diarrheal disorders: A mutation update. Hum Mutat. 2018 39(3):333-44. doi: 10.1002/humu.23386.
Jonker CTH, Galmes R, Veenendaal T, ten Brink C, van de Welle REN, Liv N, de Rooij J, Peden A, van der Sluijs P, Mardant C, Klumperman J. Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions, Nature Comm. 2018 9, doi:10.1038/s41467-018-03226-8. Link
Braakman I, Lamriben L, van Zadelhoff G, Hebert DN. Analysis of disulfide bond formation. Curr Protoc Protein Sci. 2017 90:14.1.1-14.1.21. Link
Mijnders M, Kleizen B, Braakman I. Correcting CFTR folding defects by small-molecule correctors to cure cystic fibrosis. Curr Opin Pharmacol. 2017 34:83-90. Link
Snapp EL, McCaul N, Quandte M, Cabartova Z, Bontjer I, Källgren C, Nilsson I, Land A, von Heijne G, Sanders RW, Braakman I. Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide. Elife. 2017 6. pii: e26067. Link
Kirchner S, Cai Z, Rauscher R, Kastelic N, Anding M, Czech A, Kleizen B, Ostedgaard LS, Braakman I, Sheppard DN, Ignatova Z. Alteration of protein function by a silent polymorphism linked to tRNA abundance. PLoS Biol. 2017 15(5):e2000779. Link
Radli M, Rüdiger SGD. Picky Hsp90 – every game with a different mate. Mol Cell. 2017 67:899-900 (invited preview). Link
Radli M, Veprintsev DB, Rüdiger SGD. Production and purification of human Hsp90β in Escherichia coli. PLoS One. 2017 12(6):e0180047. doi:10.1371/journal.pone.0180047. Link
Chehab T, Criado Santos N, Holthenrich A, Koerdt SN, Disse J, Schuberth C, Reza Nazmi A., Neeft M, Koch H, Man KNM, Wojcik SM, Martin TFJ, van der Sluijs P, Brose N, Gerke V. A novel Munc13-4 / S100A10 / Annexin A2 complex promotes Weibel-Palade body exocytosis in endothelial cells. Mol. Biol. Cell. 2017 28:1688-1700. Link